Posted in The History Blog
July 13, 2022

Only known pregnant Egyptian mummy had cancer

The History Blog

Researchers have discovered that a mummy in the collection of the National Museum in Warsaw that is the only known pregnant Egyptian mummy has large cavities in her face not typical of the mummification process that strongly indicate she suffered from nasopharyngeal cancer.

“When preparing the skull of the mummy we examined for 3D prints, we noticed large defects in parts of the facial bones, larger than those usually formed during mummification runs” – Marzena Ożarek-Szilke, anthropologist and archaeologist from the Medical University of Warsaw (MUU) told PAP . As she added, such smaller cavities usually arose when the brain was removed through one of the nostrils. At that time, i.a. the ethmoid bone was broken while “picking” out the brain.

Prof. Rafał Stec from the Oncology Clinic of the Medical University of Warsaw. PAP asked the scientist what proves that the Egyptian woman suffered from cancer and whether it is possible to conclude with high probability that this was the case without sampling.

“First, there are atypical changes in the nasopharyngeal bones that are not typical of the mummification process, according to experts in the study of mummies. Secondly, the opinions of radiologists based on computed tomography indicate the possibility of changes in the bones due to neoplastic causes “- the scientist pointed out. He added that the young age of the deceased and the lack of any other cause of death may very likely indicate “an oncological cause”.

The 1st century B.C. mummy inside its decorated sarcophagus was brought to Poland in December 1826 and given to the University of Warsaw to expand its nascent antiquities collection. This was the era of mummy unwrapping parties, but in a stroke of good fortune, the Warsaw mummy managed to survive the period fully wrapped and unmolested. Documentation from the 19th century claimed it was the mummy of a lady, but after World War I, researchers translated the hieroglyphics on the coffin and the inscription identified the sarcophagus’ owner as a priest named Hor-Jehuti.

That mistake was only corrected when new X-rays and CT scans taken in 2016 found that the mummy was actually an adult woman. Two years after that, a researcher examining the scans spotted an object in the pelvis region. At first she thought it might be mummification materials used to fill the abdomen, but a closer analysis of the imaging results revealed the mass had a small head, hands and a foot. It seems the natron packed into the body had all but sealed off the uterus and mineralized the fetus, preserving much of its tissue and making it visible in X-ray and CT images even though the bones largely decomposed. Scans also revealed that she was young, between 20 and 30 years old when she died, and that she had been in her early third trimester of pregnancy (26th-30th week).

Another two years of research ensued to confirm that there were no other pregnant Egyptian mummies known and the discovery was announced to the public in April 2021. Maternal and infant mortality rates were high in antiquity, so it’s surprising that there is so little evidence of it on the archaeological record in a society were mummification was so widespread. Skeletal remains of pregnant women and mummified fetuses have been found before (there were two fetuses in Tutankhamen’s tomb), but they are extremely rare.

The multi-disciplinary Warsaw Mummy Project team is still studying the mummy. They suspect she suffered from a malignant tumor, but that can only be confirmed by histopathological examination. They plan to extract tissue samples from the cavities to compare them to cancer samples found in other Egyptian mummies currently stored in US and UK tissue banks.

According to the researchers, the analysis of mummies may contribute to the development of modern medicine. As explained by prof. Stec, it will be possible to learn about the “molecular signature” of cancers and compare it with current cancers. He expressed hope that it will also broaden the knowledge about the evolution of cancer and that it may indicate further research directions in both diagnostics and treatment.

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